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Lisse - Wikipedia, the free encyclopediaLisse ( pronunciation ) is a town and municipality in the western Netherlands, in the province of South Holland. The municipality covers an area of 16.05 km2 (6.20 sq mi) of which 0.36 km2 (0.14 sq mi) is water. Its population was 22,400 in 2014. Located within the municipal boundary is also the community De Engel.